@DeSanta said in Is it possible to use Linux apps on RetroPie?:

I know RetroPie is based on Linux, but my question is: can I use apps like Firefox and Wine?

RetroPie is not based on Linux, it runs on Linux - it's not an OS by itself and it needs an existing Linux installation to work. As such, you can install other programs on it, either through apt/flatpak / compilation/etc. Do note that depending on the platform you're on (Pi5), certain applications may not be available or not working on it.